CYSTEINI HYDROCHLORIDUM MONOHYDRICUM
L-Cysteine hydrochloride monohydrate
CAS: 7048-04-6
Molecular Formula: C3H10ClNO3S
CYSTEINI HYDROCHLORIDUM MONOHYDRICUM - Names and Identifiers
| Name | L-Cysteine hydrochloride monohydrate |
| Synonyms | H-CYS-OH HCL H2O H-Cys-OH.HCl.H2O CYSTEINE HCL H2O H-Cys-OH.HCl.H_2O H-L-CYS-OH HCL H2O L-cysteine hcl monohydrate L-cysteine hydrochloride hydrate CYSTEINE HYDROCHLORIDE MONOHYDRATE L-Cystene Hydrochloride Monohydrate L-Cysteine hydrochloride monohydrate CYSTEINI HYDROCHLORIDUM MONOHYDRICUM (R)-(+)-CYSTEINE HYDROCHLORIDE HYDRATE 3-MERCAPTO-2-AMINOPROPIONIC ACID HYDROCHLORIDE 3-MERCAPTO-2-AMINOPROPIONIC ACID HYDROCHLORIDE MONOHYDRATE |
| CAS | 7048-04-6 |
| EINECS | 615-117-8 |
| InChI | InChI=1/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1 |
CYSTEINI HYDROCHLORIDUM MONOHYDRICUM - Physico-chemical Properties
| Molecular Formula | C3H10ClNO3S |
| Molar Mass | 175.63 |
| Density | 1.54 g/cm3 |
| Melting Point | 175°C |
| Boling Point | 293.9°C at 760 mmHg |
| Specific Rotation(α) | +6.0～+7.5゜ (20℃/D)(c=8,6mol/l HCl)(calculated on the dried basis) |
| Flash Point | 131.5°C |
| Water Solubility | Soluble in cold water. |
| Solubility | H2O: 1M at20°C, clear, colorless |
| Vapor Presure | <0.1 hPa (20 °C) |
| Appearance | Crystallization |
| Color | White |
| Maximum wavelength(λmax) | ['λ: 260 nm Amax: 1.0', , 'λ: 280 nm Amax: 0.3'] |
| Merck | 14,2781 |
| BRN | 5158059 |
| PH | 0.8-1.2 (100g/l, H2O, 20℃) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Stability | Stable. Incompatible with strong oxidizing agents, most common metals, hydrogen chloride. |
| Sensitive | Hygroscopic |
| Refractive Index | 6 ° (C=8, 1mol/L HCl |
| MDL | MFCD00065606 |
| Physical and Chemical Properties | Colorless to white columnar crystals or white crystalline powder, slightly special odor. Melting Point 175 °c. Soluble in water, alcohol, ammonia and acetic acid, insoluble in benzene, ether, acetone, ethyl acetate and carbon tetrachloride. The pH of the 1% aqueous solution was 1.7. It has the effect of reducing, anti-oxidation and preventing non-enzymatic browning. Mouse oral LD50 3.46mg/kg. |
| Use | Used as medicine, food, cosmetics additives |
CYSTEINI HYDROCHLORIDUM MONOHYDRICUM - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | HA2285000 |
| FLUKA BRAND F CODES | 3-10-23 |
| TSCA | Yes |
| HS Code | 29309013 |
CYSTEINI HYDROCHLORIDUM MONOHYDRICUM - Upstream Downstream Industry
| Raw Materials | L-Cystine |
CYSTEINI HYDROCHLORIDUM MONOHYDRICUM - Reference
| Reference Show more | 1. Xu Ping, Huang Min, Liao Tao, et al. Box-Behnken design Shaker-assisted response surface methodology for optimization of allicin extraction process [J]. Food Science and Technology 2019 v.44;No.335(09):277-283. 2. Song Perlin, Li Shuo, Yang Lan, et al. Optimization of extraction process, physicochemical properties and α-glucosidase inhibitory activity of sulfated polysaccharide from tumor backbones [J]. Science and Technology of food industry, 2019, 040(020):215-222. 3. Zhao Dan, Wei Chunjin, Zeng Mei, Wang Fen. Determination of N-acetyl-L-cysteine by fluorescence quenching-recovery method based on CdTe quantum dots [J]. Journal of South-Central University for Nationalities (Natural Science Edition),2017,36(04):17-21. 4. Yao Siwen, He Jiali, Zhu scientific, et al. Study on in vitro glycolysis characteristics of jackfruit polysaccharides [J]. Modern food science and technology, 2019, 035(003):87-94. 5. [IF = 4.939] Yu Cheng et al."Glutathione-Mediated clear Nanoparticles Based on ultrasall Gd2O3 for MSOT/CT/MR Imaging Guided phototherapy/Radio Combination Cancer Therapy." Mol Pharmaceut. 2019;16(8):3489-3501 |
CYSTEINI HYDROCHLORIDUM MONOHYDRICUM - Introduction
It's hygroscopic. Slow oxidation and decomposition in air. Soluble in water, ethanol and acetone. The aqueous solution is acidic. Median lethal dose (mice, abdominal cavity) 1250mg/kg.
Last Update：2022-10-16 17:28:05
CYSTEINI HYDROCHLORIDUM MONOHYDRICUM - Reference Information
| pH range of acid-base indicator discoloration | 1 - 2 |
| Overview | L-cysteine hydrochloride monohydrate is mainly used in the medical field: the prepared drug can treat leukopenia in clinic and leukopenia caused by administration of anticancer drugs and radiopharmaceuticals. It is an antidote for heavy metal poisoning, and is also used for the treatment of toxic hepatitis, thrombocytopenia and skin ulcer, and can prevent liver necrosis, treatment of bronchitis and phlegm. |
| Use | as a fermentation promoter of flour products, it accelerates the formation of gluten and prevents aging. China's provisions can be used for fermented flour products, the maximum use of 0.06g/kg. Bread improver; Nutritional supplement, antioxidant, color fixative. It has detoxification effect on propylene and aromatic poisoning, has the effect of preventing radiation injury, has the effect of treating tracheitis and resolving phlegm, has the effect of absorbing alcohol and detoxifying acetaldehyde in the body. biochemical study. Determination of calcium and magnesium in iron and steel raw materials. The reducing agent of hemolysin was determined. Growth culture and enumeration of anaerobic bacteria. used as additives in medicine, food and cosmetics |
| production method | The hair is hydrolyzed by heating with hydrochloric acid for 6~8H, the hydrochloric acid is distilled off under reduced pressure, decolorized with activated carbon, filtered, the filtrate was neutralized with aqueous ammonia to obtain crude crystals of L-cystine, and then recrystallized with aqueous ammonia to obtain L-cystine. With L-cystine as raw material, L-cysteine can be obtained by reduction, and there are two methods. Tin reduction method. Dissolve L-cystine in dilute hydrochloric acid, add tin particles and heat reflux reduction reaction 2H, filter to reduce the remaining tin particles in the solution, and diluted with water, and then saturated with hydrogen sulfide; Filter, the residue was washed with a small amount of water; The washings and filtrates were combined, concentrated under reduced pressure, cooled to crystallize, separated and dried to obtain L-cysteine hydrochloride. HOOCCH(NH2)CH2SSCH2CH(NH2)COOH Sn[HCl,H2S → HSCH2CH(NH2)COOH · CHl electrolytic reduction method L-cystine and dilute hydrochloric acid were added to the electrolytic cell, stirred and dissolved, and electrolysis at 50 Deg C; Electrolytic solution saturated with hydrogen sulfide for several hours; Filtration, filtrate plus activated carbon decolorization, decolorizing solution after reduced pressure concentration, cooling crystallization, separation, drying to L-cysteine hydrochloride, each ton of product consumption of cystine 0.7t, hydrochloric acid 1t. HOOCCH(NH2)CH2SSCH2CH(NH2)COOH HCl→HSCH2CH(NH2)COOH·CHl |
Last Update：2024-04-09 21:01:54
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Raw Materials for CYSTEINI HYDROCHLORIDUM MONOHYDRICUM